Conference Program
 
MAMMALIAN GAMETOGENESIS & EMBRYOGENESIS

July 5-10, 1998
Plymouth State College
Plymouth, NH

Chair:
John J. Eppig

Vice Chair:
Gerald M. Kidder

Session 1: Sunday PM Physiology of gametes and preimplantation embryos
Discussion leader: Jay Baltz

Jay Baltz Osmoregulatory pathways in the mouse zygote
Harvey Florman,
Tufts University School of Medicine
Calcium channel expression and function in the mouse spermatogenic lineage
Douglas Kline,
Kent State University
Attributes and dynamics of the endoplasmic reticulum in oocytes, eggs, and early embryos.

Session 2: Monday AM Cell-cell communication regulating gamete and preimplantation embryo development
Discussion leader: Jerry Kidder

Daniel Goodenough,
Harvard Medical School
Abnormal folliculogenesis in connexin37 knockout mice
Jerry Kidder,
University of Western Ontario
Arrested folliculogenesis in connexin37 knockout mice
Barbara Vanderhyden,
Ottawa Regional Cancer Center
Kit receptor and its ligand mediate cell-cell communication in the ovary
Joanne Orth,
Temple University School of Medicine

Somatic cell-germ cell interactions in the developing testis

Horacio Merchant-Larios,
Instituto de Investigaciones Biomed
Somatic cell interactions at the onset of testis differentiation
Rolf Kemler,
Max-Planck Institute for Immunobiology
Cadherin/catenin adhesion complex in early mouse development
Session 3: Monday PM Genomic modification in gametes and preimplantation embryos
Discussion leader: Marisa Bartolomei

Marisa Bartolomei,
University of Pennsylvania
Epigenetic control of H19 gene imprinting
Keith Latham,
Fels Institute, Temple University School of Medicine
Maternal Control of Embryonic Genome Function and Imprinting Effects, or: How Mothers Have the Last Word.
Jacquetta Trasler,
McGill-Montreal Children's Hospital Research Institute

Differential control of DNA methylation in the male and female germlines.

Session 4: Tuesday AM Gene expression in gametes and preimplantation embryos
Discussion leader: Carol Warner

Carol Warner,
Northeastern University
Genetic regulation of preimplantation embryo survival
Hans Scholer,
European Molecular Biology Laboratory, Heidelberg
Oct-4 gene regulation and function in the mouse germline
Jurrien Dean,
National Institutes of Health
Developmental expression of zona pellucida genes
Tom Fleming,
University of Southampton
Gene expression and epithelial differentiation in the preimplantation mouse embryo

Megan Munsie,
Monash University
Novel method in demonstrating nuclear contribution and monitoring nuclear reprogramming in mouse nuclear transfer
Session 5: Tuesday PM Regulation of meiosis
Discussion leader: Pat Hunt

Pat Hunt,
Case Western Reserve University
Chromosome behavior and meiotic cell cycle dynamics
Margaret Fuller,
Stanford University School of Medicine
Coordinate developmental control of spermatid differentiation and meiotic cell cycle progression during male gametogenesis
Nick Duesbery,
National Cancer Institute
First meiotic spindle formation
Paul Burgoyne,
National Institute for Medical Research, UK

The 'synapsis checkpoint' in male meiosis
Paula Cohen,
Albert Einstein School of Medicine
Role of mismatch repair proteins in the regulation of mammalian meiosis
Session 6: Wednesday AM Development of human gametes and preimplantation embryos
Discussion leader: Alan Handyside

David Page,
Whitehead Institute
Genetic studies of germ cell development in humans and mice
Kate Hardy,
Hammersmith Hospital
Apoptosis in the human preimplantation embryo
John Gearhart,
Johns Hopkins School of Medicine
Human primordial germ cells in culture: are they EG cells?
Jerry Schatten,
Oregon Regional Primate Research Center

Molecular reconstitution of the centrosome during human fertilization: implications for infertility

Session 7: Wednesday PM Translational and post-translational control mechanisms in germ cells and early embryos
Discussion leader: Bob Braun

Bob Braun,
University of Washington
Repression and activation of translation during murine spermatogenesis
Joel Richter,
University of Massachusetts
Translational control of early development
Norman Hecht,
University of Pennsylvania School of Medicine
RNA-binding proteins that regulate transcription, translation, and mRNA localization
Barbara Knowles,
The Jackson Laboratory
Transcript stability and controlled translation govern the oocyte/embryo transition

Mary Murray,
Wayne State University
Analysis of evolutionarily conserved germ cell translational masking mechanism
Session 8: Thursday AM Chromatin structure-function relationships in gametes and preimplantation embryos
Discussion leader: Hugh Clarke

Hugh Clarke,
Royal Victoria Hospital
Linker histone transitions during oogenesis and early embryogenesis
Alan Wolfe,
National Institutes of Health
Constraining gene commitment through chromatin modification in early embryogenesis
Richard Schultz,
University of Pennsylvania
Chromatin-based changes underlying the maternal-to-zygotic transition
Lawrence Smith,
Université de Montréal
Reprogramming of histone H1 onto chromatin after nuclear transfer transplantation
Mark Westhusin,
Texas A & M University
Gene expression in bovine embryos produced by nuclear transplantation

Ian Lyons,
University of Adelaide
Histone H2A.Z is essential for mouse development
Session 9: Thursday PM Post-banquet speaker
Ian Wilmut,
Roslin Institute
Cloning by transfer of somatic nuclei: progress, prognosis, and profit

Acknowledgements

The Ares Serono Foundation
N.V. Organon
Novo Nordisk A/S
Wyeth -Ayerst Research Laboratories
Lilly Research Laboratories


Last Updated: May 17, 2006