| SATURDAY: 6 Feb 99 |
| 6:00 |
Get together for those arriving a day early |
| SUNDAY: 7 Feb 99 |
| Chemistry of magnesium and analysis of the ionized form |
| 7:30-9:30 pm |
Chair: Professor Ursula Spichiger, ETH, Zürich, Switzerland |
|
Professor Ursula Spichiger, ETH, Zürich, Switzerland
"Recent developments in Mg2+ ionophores and electrodes" |
|
Dr. Christoph Ritter, AVL Graz, Austria
"Ionized magnesium measured with instruments using ion selective electrodes: Possibilities and limitations" |
|
Professor Ronald Elin, University of Louisville Hospital, Louisville, USA
"Overview of clinical methods for ionized magnesium determinations" |
|
Professor Lasse Larsson, Department of Clinical Chemistry, Lingköping, Sweden
"Clinical relevance of ionized magnesium measurements" |
| MONDAY: 8 Feb 99 |
| Cellular magnesium: intracellular homeostasis and membrane transport |
| 9:30-12:00 |
Chair: Professor Jürgen Vormann, Protina GmbH, Ismaning, Germany |
|
Professor M. E. Maguire, Case Western Reserve University, Cleveland, USA
"CorA and MgtC: A Ubiquitous Mg2+ Transporter and a Mg2+-regulated Virulence Factor" |
|
Dr. Dorothee Günzel, Heinrich-Heine-University, Düsseldorf, Germany
"Capacity and pH dependence of intracellular Mg2+ buffering in identified invertebrate neurones" |
|
Dr. Monika Schweigel, Free University Berlin, Germany
"Magnesium transport in ruminal epithelial cells: Putative potential-dependent and potential-independent pathways" |
|
Dr. Federica Wolf, Universita Cattolica del Sacro Cuore, Rome, Italy
"Magnesium homeostasis, cell proliferation and differentiation in HL-60 and epithelial cells" |
| Regulation of extracellular magnesium: renal and magnesium homeostasis in extracellular fluids |
| 7:30-9:30 pm |
Chair: Professor Garry Quamme, University of British Colombia, Vancouver, Canada
Introduction |
|
Professor C. de Rouffignac, Commision for Atomic Energy, Gif sur Yvette, France
"Hormonal control of renal magnesium balance" |
|
Professor Garry Quamme
"Non hormonal control of renal magnesium balance" |
|
Dr. Steven Hebert, Vanderbilt University, Nashville, USA
"Extracellular polyvalent cation-sensing" |
|
Dr. David Cole, University of Toronto, Banting Institute, Canada
"Serum magnesium and calcium are correlated with polymorphins of the Ca-sensing receptor gene in a nephrolithiasis population" |
| TUESDAY: 9 Feb 99 |
| Mechanisms for the actions of magnesium in cardiovascular disease |
| 9:30-12:00 am |
Chair: Professor John A. S. McGuigan, University of Berne, Switzerland |
|
Professor A. P. Halestrap, University of Bristol, Bristol
"The mitochondrial permeability-a pore way to die" |
|
Professor A. Scarpa, Case Western Reserve University, Cleveland, Ohio
"Intracellular Magnesium Homeostasis in Heart and Regulation of Respiration" |
|
Dr. Samuel A. Santoro, Washington University, St Louis, Missouri
"The a-2-b 1 integrin a Mg2+ dependent collagen receptor on platelets and other cells"
|
|
Professor W. Herzog, University of Maryland School of Medicine, Division of Cardiology, Baltimore, Maryland
"The effects of magnesium supplementation on myocardial reperfusion injury" |
Short
Communication |
Professor W. Weglicki, Department of Medicine and Physiology, George Washington University Medical School, Washington, DC, USA
"Magnesium and antioxidant properties" |
| Neuroscience of magnesium: basic and clinical aspects |
| 7:30-9.30 pm |
Chair: Professor Robert Vink, James Cook University of North Queensland, Australia |
|
Dr. Ibolja Cernak, Institute of Medical Research, Belgrade, Yugoslavia
""Basic and clinical aspects of magnesium's role in direct and indirect traumatic brain injury |
|
Dr. K. Michael Welch, University of Kansas Medical Center, Kansas City, USA
"The role of brain ionized magnesium in migraine" |
|
Dr. Burton M. Altura and Dr. Bella T. Altura, State University of New York, New York, USA
"Effects of alcohol and cocaine on brain: is the magnesium ion a critical factor?" |
Round Table
Discussion |
Professor Robert Vink
"Does free magnesium increase or decrease prior to neuronal death?" |
| WEDNESDAY: 10 Feb 99 |
| Magnesium transport and intracellular transduction |
| 9:30-12:00 am |
Chair: Professor Shinsuke Nakayama, Nagoya University, Nagoya, Japan |
|
Dr. Tatsu-aki Matsubara, Department of Internal Medicine III, School of Medicine,Nagoya University, Nagoya, Japan
"Modulation by insulin of intracellular free Mg2+ concentration in heart" |
|
Professor Masato Konishi, Department of Physiology, The Jikei University School of Medicine, Tokyo, Japan
"Regulation of cell magnesium by Na+- Mg2+ and Na+- Ca2+ exchange" |
|
Professor Hideki Gotoh, Department of Biological Technology, Soka University, Tokyo, Japan
"Intracellular magnesium surge due to depolarization in cultured neurons" |
|
Dr. Joseph Clark, Department of Biochemistry, Oxford University, UK
"Magnesium and protection of vascular smooth muscle" |
Short
Communication |
Dr. Junji Watanabe, Department of Internal Medicine III, School of Medicine, Nagoya University, Nagoya, Japan
"Regulation of intracellular free Mg2+ concentration via beta-adrenergic and muscarinic receptors in heart" |
|
Dr. Michiko Tashiro, Department of Physiology, The Jikei University School of Medicine, Tokyo, Japan
"Modulation of cardiac excitation-contraction coupling by cytosolic [Mg2+]" |
| Magnesium, catecholamines and stress |
| 7:30-9:30pm |
Chair: Professor Sepp Porta, University of Graz and Institute of Applied Stress Research, Bad Radkersburg, Austria |
|
Professor Sepp Porta
Introduction |
|
Professor Helmwart Zollner, Institute of Biochemistry, University of Graz
"Biochemical aspects of Mg2+ - catecholamine interaction, old and recent data" |
|
Professor A. Epple, Thomas Jefferson Medical School, Philadelphia
"Catecholamine reactions to Mg2+ supplementation in animal experiments - a pathophysiological approach" |
|
Dr. Karl-Heinz Smolle, Department Medicine, Graz, Austria
"Role of Mg2+ in stress and exhaustion: new assessment methods by simultaneous blood gas and electrolyte screening of large groups" |
|
Professor Sepp Porta
"Final remarks, Mg2+ as a regulator of carbohydrate and catecholamine turnover" |
| THURSDAY: 11 Feb 99 |
| Actions of magnesium |
| 9:30-12:00 am |
Chair: Dr. Ron Smith, Department of Biology, University of Texas at Arlington, Arlington, Texas |
|
Dr. Robin Preston, Department of Physiology, Medical College of Pennsylvania, Philadelphia, PA, USA
"Mg induced behavior in paramecium" |
|
Professor William Weglicki, Department of Medicine and Physiology, George Washington University, Washington, DC, USA
"Neurogenic inflammation due to Mg deficiency" |
|
Professor L. Resnick, Division of Endocrinology / Hypertension, Wayne State University Medical Center, Detroit, MI, DC, USA
"Regulation of intracellular free magnesium in health and disease: relation to aging" |
|
Dr. Ron Smith, University of Texas at Arlington, Texas, USA
"The role of Mg and the Mg transporters on Salmonell virulence" |
|
Two short communications from younger scientists selected from the poster sessions |
| Chronic latent magnesium deficiency (CLMD): fact or fiction |
| 7:30-9.30 pm |
Chair: Professor Ron E. Elin, University of Louisville Hospital, Louisville, USA |
|
Dr. Robert Rude, University of Southern California, Los Angeles, USA
"The diagnosis and treatment of chronic latent magnesium deficiency" |
|
Professor P.C. Elwood, MRC Unit, Llandough Hospital, Penarth, Wales
"Chronic latent magnesium deficiency: minimum risk to health?" |
|
Dr. Mildred Seelig, 1052D North Jamestown Road, Georgia, USA
"Chronic latent magnesium deficiency: significant risk to health?" |
|
Professor Ron E. Elin, University of Louisville Hospital, Louisville, USA
"Overview of CLMD" |
| FRIDAY: 12 Feb 99 |
|
End of conference
|