| Sunday - July 16, 2000 |
| 6:00 pm |
Dinner |
| Session 1 |
| Jean Suffert, Discussion Leader |
| |
John Hartwig, Yale University
Metal-Catalyzed C-N, C-O ad C-C Bond Forming Reactions and How They Work |
| |
Paul Wender, Stanford University
Toward the Ideal Synthesis: New Strategies and New Reactions Inspired by New Medicinal Leads |
| Monday - July 17, 2000 |
| 7:30 am |
Breakfast |
| Session 2 |
| Donald Hou, Discussion Leader |
|
Rick Danheiser, Massachusetts Institute of Technology
New Annulation Strategies Based on Highly Unsaturated, Conjugated Molecules
|
|
Agnes Kim-Meade, Schering-Plough Research Institute
Discovery and Development of a Novel Enantioselective Alkylation Reaction and Its Application Towards the Synthesis of the Farnesyl Protein Transferase Inhibitor Sch 66336
|
| Session 3 |
| Steven Nolan, Discussion Leader |
| |
Gerald Hammond, University of Massachusetts-Dartmouth
Green Flourinations: selective flourine incorporation in aqueous media using a flouroorganometallic building block |
|
Shon Pulley, University of Missouri-Columbia
Diversely Functionalized Aromatics via Benzannulation
|
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David Gin, University of Illinois
New Methods in Carbohydrate Synthesis
|
| 12:30 |
Lunch |
| 4:00 - 6:00 |
Poster Session 1 |
| 6:00 |
Dinner |
| Session 4 |
| Mukund Sibi, Discussion Leader |
|
Janine Cossy, Laboratoire de Chimie Organique, ESPCI
New Methodologies and their Application to the Synthesis of Biologically Active Compounds
|
| |
P. Andrew Evans, University of Delaware
Regioselective Rhodium-Catalyzed Allylic Substitution Reactions |
| |
Albert Padwa, Emory University
Application of Tandem Processes for Alkaloid Synthesis |
| Tuesday - July 18, 2000 |
| 7:30 am |
Breakfast |
| Session 5 |
| Edward Delaney, Discussion Leader |
| |
Nicos Petasis, University of Southern California
New Reactions of Organoboronic Acids |
|
Marisa C. Kozlowski, University of Pennsylvania
Synthesis and Application of Novel Cis-Decalin Type Chiral Ligands |
| Session 6 |
| Mathias McIntosh, Discussion Leader |
| |
Jin Cha, University of Alabama
Small Ring-Mediated Organic Synthesis |
|
Ioannis N. Houpis, Merck Research Laboratories
Diastereoselective Michael Reaction, Gem-Difluorination and Cu-Catalyzed Aromatic Amination in the Synthesis of a Complex Drug Candidate |
| 12:30 |
Lunch |
| 1:30 |
Annual OR&P Golf "Classic" |
| Session 7 |
| Christopher Schmid, Discussion Leader |
|
Armin deMeijere, Georg August Universität Göttingen
New Pd-Catalyzed Cascade Reactions and Ti-Mediated C,C-Bond Formations for Organic Synthesis |
| |
Margaret Faul, Eli Lilly and Company
New Methods for the Synthesis of Bisindolylmaleimides Indolocarbazoles |
| |
Stephane Caron, Pfizer
Process Research Towards an Synthesis of a PDE4/TNFa Inhibitor for the Treatment of Inflammatory Disease |
| |
Business Meeting and Nominations |
| Wednesday - July 19, 2000 |
| 7:30 am |
Breakfast |
| Session 8 |
| Kay Brummond, Discussion Leader |
| |
James R. Gage, Upjohn
Large Scale Synthesis of a New Class of Oxazolidinones |
| |
Scott Miller , Boston College
Discovery of Minimal Peptides for Asymmetric Catalysis and Organic Synthesis |
| |
Paul Hanson, University of Kansas
Metathesis Approaches to Diverse Phosphorus and Sulfur Motifs |
| Session 9 |
| Richard Pariza, Discussion Leader |
|
Frederick West, University of Utah
Novel Applications of the Nazarov Cyclization: Domino Processes and Stereochemical Issues |
|
Marc Snapper, Boston College
Cyclobutadienes in synthesis |
| 12:30 |
Lunch |
| 4:00 - 6:00 |
Poster Session 2 |
| 6:00 |
Dinner |
| Session 10 |
| Robert Malezcka, Discussion Leader |
| |
Keiji Maruoka, Hakkaido University
Bidentate, Chiral Lewis Acids for Catalytic Asymmetric Synthesis |
| |
Richard Hsung, University of Minnesota
Organic Reactions Using Chiral Allenamides |
| |
Jonathan Clayden, University of Manchester
Sterocontrol and Synthesis with Rotationally Restricted Amides |
| Thursday - July 20, 2000 |
| 7:30 am |
Breakfast |
| Session 11 |
| Mezzie Ash, Discussion Leader |
| |
Keith Woerpel, University of California-Irvine
New Methods for Stereoselective Synthesis Based Upon the Reactions of Silacyclopropanes |
|
Benzin Zhi, Searle
Process Development of Celebrex |
| Session 12 |
| Robert B. Grossman, Discussion Leader |
| |
Eckhard Ottow, Schering AG
Synthesis of Competitive AMPA-Antagonist ZK 200775 - Optimization and Scale Up |
| |
David Crich, University of Illinois-Chicago
The Non-Oxidative Pathway to Alkene Radical Cations; Mechanism, Stereochemistry and Application |
| 12:30 |
Lunch |
| 2:00 |
Annual Academic / Industrial Softball Game |
| 4:00 - 6:00 |
Chair's Reception - Wine Tasting |
| 6:00 |
Dinner |
| Session 13 |
| Michael F. Lipton, Discussion Leader |
| |
Kenneth Miller, Brown University
The Evolution of Complex Biochemical Systems |
| |
Closing Remarks |
| Friday - July 21, 2000 |
| 7:30 am |
Breakfast |
| 9:00 |
GRC Chartered Bus Departs for Boston |