| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 5:00 pm - 6:00 pm | Wine Social |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Genomics I |
| 7:30 pm - 7:50 pm | Welcoming address & Scientific Overview: Sjõlander & Stephanopoulos |
| Ewan Birney (EBI)
"New methods in comparative genomics" |
| Edison Liu (GIS)
"Digital Biology: Social integration of biology and mathematical sciences" |
| MONDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Genomics II |
| Session Chair: Ewan Birney |
| Craig Benham (UC Davis)
"Roles of Structural Transitions in Mechanisms of DNA Regulation" |
| John Weinstein (National Cancer Institute)
"Integromic analysis in cancer diagnostics and drug discovery" |
| 10:25 am - 10:45 am | Coffee break |
| Sandro Jose de Souza (Ludwig Institute For Cancer Research, Brazil)
"Large-scale analysis of intron retention events in the human transcriptome" |
| Richard Durbin (Sanger Centre)
"Using context and phylogeny to extend HMM methods for protein domains" |
| Zemin Zhang (Genentech)
"From ESTs to Cancer Therapeutic Targets" |
| 12:45 pm | Group Photo / Lunch |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Pathways & Networks I |
| Session Chair: Isidore Rigoutsos, IBM |
| Donna Slonim (Genetics Institute)
"Pathway inference from expression and sequence data" |
| Adam Arkin (UC Berkeley)
"Playing practical games with bacteria and viruses. Exploring the molecular mechanisms behind clever cellular stratagems."
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| Steven Brenner (UC Berkeley)
"Alternative splicing and gene regulation" |
| TUESDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Pathways & Networks II |
| Session chair: Donna Slonim |
| Vassily Hatzimanikatis (Northwestern U.)
"Discovery of novel metabolic networks" |
| Matthias Reuss (Stuttgart)
"System-oriented dynamic modeling of Saccharomyces cerevisiae: Coupling cell cycle progression and energy metabolism" |
| 10:25 am - 10:45 am | Coffee break |
| Greg Stephanopoulos (MIT)
"Analysis and Quantification of Metabolic Bioreaction Networks." |
| Doraiswami Ramkrishna (Purdue)
"A Cybernetic Approach to Analysis of Metabolic Regulation in Large Pathways: An Evolving Framework for Bioinformatics" |
| Jim Fickett, AstraZeneca
"Systems Biology, Drug Discovery, and EGF signalling" |
| 12:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Poster session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Selected short talks from posters |
| Session chair: Drew Endy |
| WEDNESDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Proteomics |
| Session chair: Ian Holmes, Oxford University |
| Matthias Mann (Univ. of Southern Denmark)
"Protein interaction studies by mass spectrometry based proteomics" |
| Ed Marcotte (U. Texas)
"Reconstructing the global organization of yeast proteins" |
| 10:25 am - 10:45 am | Coffee break |
| Tanja Kortemme (U. Washington, Seattle)
"Specificity in protein-protein recognition - prediction and design" |
| Peer Bork (EMBL-Heidelberg)
"Function prediction and protein networks" |
| Selected talk from posters |
| 12:30 pm | Lunch |
| 4:30 pm - 6:00 pm | Poster session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Proteins: structure, function, and evolution |
| Session chair: Chris Ponting, Oxford University |
| Olivier Lichtarge (Baylor College of Medicine)
"Phylogenomics at work: engineering G protein signaling based on functional site characterization" |
| Kimmen Sjõlander (UC Berkeley)
"High-throughput phylogenomic analysis for protein functional classification: new methods for an old task" |
| Jeffrey Skolnick (Univ. of Buffalo)
"Prediction of protein structure and function on a genomic scale" |
| THURSDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Bioinformatics and systems biology |
| Session chair: Matthias Mann (Univ. of Southern Denmark) |
| Shankar Subramaniam (UCSD)
"Reconstruction and Modeling of Networks from Cellular Data" |
| Hans van Beek Center for Medical Systems Biology, The Netherlands
"Computational Analysis of a Single Pre-Steady-State 13C NMR Spectrum to Quantitate Metabolic Flux" |
| 10:25 am - 10:45 am | Coffee break |
| Shoshana Wodak (U. Libre de Bruxelles, Belgium)
"Multi-protein complexes and their transcriptional regulation in yeast: what can we learn from genome-scale studies?" |
| Michael Eisen (Lawrence Berkeley Laboratory)
"Evolution of cis-Regulation in Eukaryotes" |
| Eric Neumann (Beyond Genomics, Inc.)
"Applications of Differential Analysis to Molecular and Clinical Systems Biology" |
| 12:30 pm | Lunch |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | New directions in Bioinformatics |
| Session chair: Shankar Subramaniam, UCSD |
| Lisa Vawter (Aventis Pharmaceuticals)
"Chemical Biology" |
| Isidore Rigoutsos (IBM)
"Of Parts and Relationships: Pattern Discovery at Work" |
| 10:00 pm - | Party |
| FRIDAY |
| 7:45 am - 8:30 am | Breakfast |
| 9:00 am | Depart |