Conference Program
 
EVOLUTIONARY & ECOLOGICAL FUNCTIONAL GENOMICS

August 3-8, 2003
Colby-Sawyer College
New London, NH

Chair:
Martin Feder

Vice Chair:
Thomas Mitchell-Olds

Genomics and its successor approaches (transcriptomics, proteomics, etc.) are discovering remarkable variation in genes and their expression - but these discoveries are only the first step. The next step is discovering if/how/why this variation matters; i.e., affects the function and fitness of whole organisms in populations. Alongside the already well-established communities in biomedical and agricultural functional genomics, a new community is forming: evolutionary and ecological functional genomics, which seeks to understand the functional significance of genomic variation for wild organisms (microbial, plant, and animal) in natural biological communities. Doing so requires elucidating the biotic and abiotic challenges to function in natural environments, the molecular and cellular mechanisms used to meet these challenges, and the evolutionary mechanisms/processes that manipulate these mechanisms through time. Bringing ecological, functional, genomic, and evolutionary investigation to bear on a single species - sometimes a 'non-model' species' - can be a massive undertaking, and this community is presently grappling with how to mount such interdisciplinary efforts collaboratively and train young scientists to do so. This Gordon Research Conference is intended to be the conference of record for this community. It would (1) showcase the successes and achievements of the field to date; (2) examine novel models of collaboration, interdisciplinary training, and information management; (3) map out future directions and priorities.

The following is the program as of 10 July 2003. Revised programs will be posted if revisions are made.


SUNDAY
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 9:30 pmIF EVOLUTIONARY & ECOLOGICAL FUNCTIONAL GENOMICS IS THE ANSWER, WHAT IS THE QUESTION?
7:30 pm - 7:40 pmMartin Feder (University of Chicago)
"Introduction to the conference"
7:40 pm - 8:15 pmMay Berenbaum (University of Illinois)
"Populogenomics, communigenomics, and ecogenomics--are there such beasts?"
8:15 pm - 8:25 pmDiscussion
8:25 pm - 9:00 pmAndrew Clark (Cornell University)
"Unanswered questions in evolutionary functional genomics not revealed by Drosophila innate immunity because we actually do answer some of the questions"
9:00 pm - 9:10 pmDiscussion
9:10 pm - 9:30 pmGeneral discussion
9:30 pm - Reception
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmOUTCOMES OF NATURAL AND ENGINEERED EVOLUTION
Discussion Leader: Antony Dean (University of Minnesota)
9:00 am - 9:10 amIntroduction to session
9:10 am - 10:00 amJohn Doyle (California Institute of Technology)
"On evolving robustness"
10:00 am - 10:30 amCoffee Break / Group Photograph
10:30 am - 10:45 amDiscussion
10:30 am - 10:55 amSteven Benner (University of Florida)
"Finding Genes that Matter using Planetary Biology: Towards a Global Genome Annotation"
10:55 am - 11:00 amDiscussion
10:45 am - 11:20 amSteven Benner (University of Florida)
"Finding Genes that Matter using Planetary Biology: Towards a Global Genome Annotation"
11:20 am - 11:30 amDiscussion
11:30 am - 12:05 pmClaudia Schmidt-Dannert (University of Minnesota)
"Nature's strategies of gene evolution and gene combination applied to cell factory engineering"
12:10 pm - 12:20 pmDiscussion
12:20 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmEXPLOITING LINKAGES TO OTHER DISCIPLINES
Discussion Leader: Jack Schultz (Pennsylvania State University)
7:30 pm - 7:40 pmIntroduction to session
7:40 pm - 8:20 pmBrad Gibson (Buck Institute)
"Developing new chemical tools for proteome-wide analyses"
8:20 pm - 8:35 pmDiscussion
8:35 pm - 9:15 pmLeroy Hood (Institute for Systems Biology)
"Systems Biology, Evolution and Complexity"
9:15 pm - 9:30 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmECOLOGY: MODEL SYSTEMS VS. NON-MODEL SYSTEMS
Discussion Leader: Wayne Potts (University of Utah)
9:00 am - 9:15 amIntroduction to session
9:15 am - 9:55 amCraig Cary (University of Delaware)
"A meta-genome level analysis of an complex microbial symbiosis from an extreme environment"
9:55 am - 10:05 amDiscussion
10:05 am - 10:25 amCoffee Break
10:25 am - 10:55 amLisa Donovan (University of Georgia)
"Stressful living and trait evolution in Helianthus hybrid species"
10:55 am - 11:00 amDiscussion
11:00 am - 11:30 amJohanna Schmitt (Brown University)
"Selection at specific loci in Arabidopsis in natural environments"
11:30 am - 11:35 amDiscussion
11:35 am - 12:05 pmThomas Mitchell-Olds (Max Planck Institute for Chemical Ecology)
"Functional evolutionary genetics of Arabidopsis"
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmINSIGHTS FROM EVOLUTIONARY INFORMATICS AND POPULATION BIOLOGY
Discussion Leader: Michael Purugganan (North Carolina State University)
7:30 pm - 7:45 pmIntroduction to the session
7:45 pm - 8:10 pmDavid Pollock (Louisiana State University)
"Mechanism, structure, and context-dependent evolutionary processes"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmHopi Hoekstra (University of Arizona/University of California San Diego)
"The genetic basis of adaptation in natural populations: lessons from pigmentation genes in pocket mice"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmJeffrey Townsend (University of California Berkeley)
"Population variation in gene expression at a genomic scale"
9:20 pm - 9:30 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmWHAT CAN TRANSCRIPTOMICS REALLY CONTRIBUTE TO EVOLUTIONARY & ECOLOGICAL FUNCTIONAL GENOMICS?
Discussion Leader: Andrew Cossins (University of Liverpool)
9:00 am - 9:15 amIntroduction to session: "Some principles of comparative transcript profiling - scale, technique and pattern analysis"
9:15 am - 9:50 amRichard Lenski (Michigan State University)
"Discovery by transcriptomics and other approaches of genes underlying adaptation during 20,000 generations of experimental evolution with E. coli"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amCoffee Break
10:20 am - 10:55 amGreg Gibson (North Carolina State University)
"Quantitative transcriptomics: drift and association at the level of expression"
10:55 am - 11:05 amDiscussion
11:00 am - 11:35 amGreg Wray (Duke University)
"Evolutionary changes in transcriptional regulation in primates: identifying the genes that make us human"
11:35 am - 11:45 amDiscussion
11:45 am - 12:15 pm Justin Borevitz, The Salk Institute
"Microarray Evolution: Expression to Mapping and Back Again"
12:15 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session III
6:00 pmDinner
7:30 pm - 9:30 pmDEVELOPMENT IN EVOLUTIONARY AND ECOLOGICAL CONTEXT
Discussion Leader: Paul Brakefield (University of Leiden)
7:30 pm - 7:45 pmIntroduction to the session
7:45 pm - 8:10 pmDavid Kingsley (Stanford University)
"The genetic architecture of morphological evolution in threespine sticklebacks"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmPaul Rainey (University of Auckland/Oxford University)
"Mapping the connection between genotype, phenotype and fitness in a model adaptive radiation"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmClaude de Pamphlis (Pennsylvania State University)
"The Floral Genome Project: The origin and diversification of the floral genetic program"
9:20 pm - 9:30 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNEW DIRECTIONS IN EVOLUTIONARY AND ECOLOGICAL FUNCTIONAL GENOMICS
Discussion Leader: Albert Bennett (University of California, Irvine)
9:00 am - 9:30 amCristian Castillo-Davis (Harvard University)
Marie-Anne Felix (Institut Jacques Monod)
Michael Herman (Kansas State University)
Vaishali Katju (Indiana University)
and/or W. Kelley Thomas (University of New Hampshire)
"Nematodes: the next big model system for evolutionary and ecological functional genomics?"
9:30 am - 9:50 amMartin Feder (University of Chicago)
Thomas Mitchell-Olds (Max Planck Institute for Chemical Ecology)
BUSINESS MEETING
9:50 am - 10:10 amJoshua B. Plotkin (Harvard University)
"The evolutionary ecology of Influenza A viruses"
10:10 am - 10:30 amCoffee break
10:30 am - 10:50 amWayne K. Potts (Department of Biology, University of Utah)
"Functionally equivalent" HOX translocation shows strong fitness defect in "nature"
10:50 am - 11:10 amDimitri Petrov (Stanford University)
"Searching for adaptive transpositions: a possible case of transposable element induced pesticide resistance in Drosophila melanogaster"
11:10 am - 11:30 amDavid Guttman (University of Toronto)
"Evolutionary and functional genomics of the Type III secretion system"
11:30 am - 11:50 amLeonid L. Moroz (The Whitney Laboratory, University of Florida)
"Large-scale gene expression profiling at the level of single neurons and their synapses in functionally defined networks of marine, land and freshwater molluscan species: genomic profiling of homologous neurons and evolution of neuronal signaling pathways"
11:50 am - 12:10 pmMarina Caillaud (Ithaca College)
"Differential gene expression between alfalfa and clover specialists in two incipient species of the herbivorous insect Acyrthosiphon pisum"
12:10 pm - 12:30 pmHeidi Appel (Pennsylvania State University)
"Signals crossed: exploring signaling pathway function in Arabidopsis responses to insects"
12:30 pmLunch
1:30 pm - 6:00 pmFree Time
6:00 pmDinner
7:30 pm - 9:30 pmFUNCTIONAL ANALYSIS AS INFORMED BY ECOLOGY, EVOLUTION, AND GENOMICS
Discussion Leader: Ian Johnston (University of St. Andrews)
7:30 pm - 7:45 pmIntroduction to the session
7:45 pm - 8:10 pmRichard ffrench-Constant (University of Bath)
"Finding genes involved in natural selection"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmLauren Ancel Meyers (University of Texas, Austin)
"How thermodynamic constraints affect evolutionary dynamics"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmGene Robinson (University of Illinois)
"Genomics and Integrative Analyses of Division of Labor in Honey Bee Colonies"
9:20 pm - 9:30 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

Last Updated: May 4, 2006