| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GENOME STRUCTURE |
| Chair: Aravinda Chakravarti (Johns Hopkins University)
Each talk has 10 minute discussion |
| 7:30 pm - 8:30 pm | Keynote Speaker: Eric Lander (Whitehead Institute, MIT)
"Comparative Genomics" |
| 8:30 pm - 9:00 pm | Evan Eichler (Case Western Reserve University)
"Segmental Duplications and the Human Genome" |
| 9:00 pm - 9:30 pm | Eric Green (National Human Genome Research Institute)
"New Frontiers in Comparative Sequencing" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | FUNCTIONAL DISSECTION OF THE HUMAN GENOME |
| Chair: Eddy Rubin (University of California, Berkeley)
Each talk has 10-minute discussion |
| 9:00 am - 9:30 am | Chris Burge (Massachusetts Institute of Technology)
"Bioinformatics of MicroRNAs" |
| 9:30 am - 10:00 am | Thomas Gingeras (Affymetrix, Inc)
"Evidence of Hidden Transcriptome and Strategies Employed to
Regulate Expression of RNA Transcripts" |
| 10:00 am - 10:30 am | Harry Dietz (Howard Hughes Medical Institute)
"Physiologic Substrates for mRNA Surveillance: Mechanistic and
Therapeutic Implications" |
| 10:30 am | Coffee Break / Photo |
| 11:00 am - 11:30 am | Eddy Rubin (University of California, Berkeley)
"Trolling Vertebrates and Beyond for Gene Regulatory Insights" |
| 11:30 am - 11:45 am | John Stamatoyannopoulos (Regulome Corporation)
"High-Throughput Identification of Regulatory Elements in the Human Genome" |
| 11:45 am - 12:00 pm | Jessica Alfoldi (Whitehead Institute)
"Sequence of the Mouse Y Chromosome" |
| 12:00 pm - 12:30 pm | General discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GENOME AND HUMAN EVOLUTION |
| Chair: Evan Eichler (Case Western Reserve University)
Each talk has 10-minute discussion |
| 7:30 pm - 8:00 pm | Philip Green (University of Washington)
"Signal and Noise in Genome Sequences" |
| 8:00 pm - 8:30 pm | Arend Sidow (Stanford University)
"Protein Evolution and the Deleteriousness of cSNPs" |
| 8:30 pm - 9:00 pm | Barbara Trask (Fred Hutchinson Cancer Research Center)
"Dynamic Duplications in the Human Genome" |
| 9:00 pm - 9:30 pm | Svante Paabo (Max Planck Institute)
"Comparative Transcriptomics in Primates"
|
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MECHANISMS OF GENOMIC DISEASE |
| Chair: Barbara Trask (Fred Hutchinson Cancer Research Center)
Each talk has 10-minute discussion |
| 9:00 am - 9:30 am | James Lupski (Baylor College of Medicine)
"Genome Architecture, Rearrangements, Evolution and Genomic
Disorders" |
| 9:30 am - 10:00 am | Bernice Morrow (Albert Einstein College of Medicine)
"The Dynamic Nature of Low Copy Repeats on 22q11 (LCR22) in
Shaping Genomic Architecture and Causing Genetic Disorders" |
| 10:00 am - 10:30 am | Donna Albertson (University of California San Francisco)
"DNA Copy Number Analyses in Cancer and Medical Genetics using Array CGH" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Mary Bedell (University of Georgia, Athens)
"Effects of Noncoding Mutations on Gene Function: Examples from the Kit Ligand Gene of Mice" |
| 11:30 am - 11:45 am | Mary Rudd (Duke University)
"Organization of Centromeric DNA on Human Chromosome 17"
|
| 11:45 am - 12:00 pm | Nicholas Katsanis (Johns Hopkins University)
"Bardet-Biedl Syndrome (BBS)" |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 5:00 pm | NIH Grant Discussion (Camilla Day) |
| 5:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MOLECULAR AND FUNCTIONAL VARIATION |
| Chair: David Altshuler (Harvard Medical School)
Each talk has 10-minute discussion |
| 7:30 pm - 8:00 pm | Debbie Nickerson (University of Washington)
"Genic Sequence Variation" |
| 8:00 pm - 8:30 pm | Pui Kwok (University of California, San Francisco)
"Large-scale SNP Genotyping and Haplotyping Technologies" |
| 8:30 pm - 9:00 pm | David Bentley (Wellcome Trust Sanger Institute)
"Human Haplotype Variation" |
| 9:00 pm - 9:30 pm | Peter Donnelly (University of Oxford)
"Fine-scale recombination mapping of the human genome" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | MOLECULAR GENETIC EPIDEMIOLOGY |
| Chair: Debbie Nickerson (University of Washington)
Each talk has 10-minute discussion |
| 9:00 am - 9:30 am | Nancy Cox (University of Chicago)
"Approaches to Identifying Genetic Variation Affecting Susceptibility to Complex Disorders" |
| 9:30 am - 10:00 am | Steve O'Brien (National Cancer Institute)
"HIV Susceptibility" |
| 10:00 am - 10:30 am | David Cutler (Johns Hopkins University)
"Prospects and Methods for Whole Genome Association Studies" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Alan Doyle (The Wellcome Trust)
"UK Biobank - A Genetic Database for Research" |
| 11:30 am - 11:45 am | Emily Walsh (Whitehead Institute)
"An Integrated Haplotype Map of the Human Major Histocompatibility Complex"
|
| 11:45 am - 12:00 pm | James Scott (Imperial College of London)
"Biological Atlas of Insulin Resistance (BAIR)"
|
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Larry Adelman (California NewsReel)
Viewing and Discussion of "The Difference Between Us" |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| 7:30 pm - 9:30 pm | GENE IDENTIFICATION IN COMPLEX DISEASE |
| Chair: Huntington Willard (Duke University)
Each talk has 10-minute discussion |
| 7:30 pm - 8:00 pm | Eric Boerwinkle (University of Texas Health Sciences Center)
"Human Hypertension Genes" |
| 8:00 pm - 8:30 pm | David Altshuler (Harvard Medical School)
"Characteristics and Applications of Haplotypes in the Human Genome" |
| 8:30 pm - 9:00 pm | Stylianos Antonarakis (University of Geneva Medical School)
"The Mystery of Conserved, Non-Genic (CNGs) Sequences" |
| 9:00 pm - 9:30 pm | Monica Justice (Baylor College of Medicine)
"Mouse Mutagenesis: Defining Gene Function and Modeling Human
Disease" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CHROMOSOME BIOLOGY AND EPIGENETICS |
| Chair: James Lupski (Baylor College of Medicine)
Each talk has 10-minute discussion |
| 9:00 am - 9:30 am | Jeannie Lee (Harvard Medical School)
"The Regulation of X-chromosome Inactivation by Noncoding RNA Loci" |
| 9:30 am - 10:00 am | Huntington Willard (Duke University)
"Centromeres and Second-Generation Artificial Chromosomes" |
| 10:00 am - 10:30 am | Beth Sullivan (Boston University)
"Organization of Centromeric Chromatin in Humans and Flies" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Aravinda Chakravarti (Johns Hopkins University)
"Genetics and Epigenetics of Complex Disease" |
| 11:30 am - 11:45 am | Mary Schuler (National Human Genome Research Institute)
"Evolution of a Functional Primate Centromere"
|
| 11:45 am - 12:00 pm | David Martin (Victor Chang Cardiac Research Institute)
"Epigenetic Slilencing" |
| 12:00 pm - 12:30 pm | General discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CONCLUDING SESSION |
| Chair: Eric Green (NHGRI) |
| 7:30 pm - 8:30 pm | Keynote Speaker: Kay Davies
"ENU mutagenesis in the elucidation of novel genes involved in movement and behaviour" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |