| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Tribute to Bert Holland: Microbial Biotransformations |
| session chair: J. Bryan Jones, University of Toronto |
| 7:30 pm - 8:05 pm | Jack Rosazza, University of Iowa
Nocardia sp. carboxylic acid reductase: cloning, expression,
characterization, mechanism and use |
| 8:05 pm - 8:40 pm | Jim Spain, Tyndall AFB
Biocatalysts from catabolic pathways
|
| 8:40 pm - 9:15 pm | Derek Boyd, Queen's University
Recent oxidoreductase-catalysed routes to enantiopure organosulfur compounds
|
| 9:15 pm - 9:30 pm | discussion |
| 9:30 pm | Reception |
| Monday |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Photo |
| 9:00 am - 12:00 pm | Pushing the Envelope on Biocatalyst Performance |
| session chair: Ichiro Matsumura, Emory University |
| 9:00 am - 9:35 am | Don Hilvert, ETH Zurich
Molecular diversity and catalysis |
| 9:35 am - 10:10 am | Peter Halling, University of Strathclyde
Enzyme action at and near solid interfaces - immobilized substrates and mainly solid reaction systems |
| 10:10 am - 10:35 am | coffee break |
| 10:35 am - 11:10 am | Nick Turner, University of Edinburgh
Deracemisation reactions using combined chemo/bio-catalytic approaches |
| 11:10 am - 11:45 am | Andrés Illanes, Universidad Católica de Valparaíso
The impact of thermal deactivation on enzyme reactor performance
|
| 11:45 am - 12:00 pm | discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Novel Biocatalysts |
| session chair: Jon Stewart, University of Florida |
| 7:30 pm - 8:05 pm | Aubrey Jones, Novozymes Biotech
Directed evolution of a maltogenic alpha-amylase; optimizing for a low pH, high temperature application |
| 8:05 pm - 8:40 pm | Shotaro Yamaguchi, Amano
A novel protein modification enzyme: protein-glutaminase |
| 8:40 pm - 9:15 pm | Wolfgang Kroutil, University of Graz
Racemases and sulfatases for deracemisation |
| 9:15 pm - 9:30 pm | discussion |
| Tuesday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:00 pm | Combinatorial Biocatalysis/High-Throughput Screening |
| session chair: Bernhard Hauer, BASF |
| 9:00 am - 9:35 am | Uwe Bornscheuer, University of Greifswald
Biocatalysis with lipases and esterases: challenges and discoveries in the synthesis of optically pure compounds and in lipid modification |
| 9:35 am - 10:10 am | Dan Robertson, Diversa
Nitrilase discovery and evolution: strategies and insights for accessing chirality |
| 10:10 am - 10:35 am | coffee break |
| 10:35 am - 11:10 am | Bill Coleman, Kairos Scientific
Application of solid-phase, high-throughput screening technology to enzyme evolution |
| 11:10 am - 11:45 am | Andrew Griffiths, MRC Laboratory of Molecular Biology
Directed evolution of enzymes using in vitro compartmentalisation (IVC) |
| 11:45 am - 12:00 pm | discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Biocatalysis for Biomaterials |
| session chair: David R. Dodds, Dodds & Associates LLC |
| 7:30 pm - 8:05 pm | Richard Gross, Brooklyn Polytechnic University
New opportunities for enzymes as catalysts for the synthesis and
modification of polymers |
| 8:05 pm - 8:40 pm | Kurt F. Brandstadt, DowCorning
An enzyme catalyzed reaction at silicon |
| 8:40 pm - 9:15 pm | Shiro Kobayashi, Kyoto University
Enzymatic polymerization for precision synthesis of polysaccharides |
| 9:15 pm - 9:30 pm | discussion |
| Wednesday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:00 pm | Whole-Cell vs. Isolated Enzymes |
| session chair: Alex Zaks, Schering-Plough |
| 9:00 am - 9:35 am | Susan Truesdell, Pfizer Inc.
Microbial biotransformation for synthesis of drug metabolites and pharmaceutical intermediates |
| 9:35 am - 10:10 am | John Woodley, University College London
Baeyer-Villiger monooxygenase biocatalysis: Comparison of whole-cell and isolated enzyme based processes |
| 10:10 am - 10:35 am | coffee break |
| 10:35 am - 11:10 am | Oliver May, Degussa
Hydantoinase technology - from liver extract to designer bugs |
| 11:10 am - 11:45 am | Andreas Schmid, ETH Hönggerberg
Cell free systems, electroenzymology & whole cell efficiency: new prospects of oxygenase biocatalysis |
| 11:45 am - 12:00 pm | discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Performance Comparisons between Chemical and Biological Catalysts |
| session chair: Jim Lalonde, Codexis |
| 7:30 pm - 8:05 pm | Roger Sheldon, Technical University, Delft
Green chemistry and catalysis: chemo or bio? |
| 8:05 pm - 8:40 pm | Andeas Liese, University of Münster
Processes with enzymes and chemzymes - comparison from a reaction engineering viewpoint |
| 8:40 pm - 9:15 pm | Stan Roberts, University of Liverpool
The A, B, C of catalysis - an overview of the different approaches |
| 9:15 pm - 9:30 pm | discussion |
| Thursday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:00 pm | Engineering of Biocatalytic Pathways |
| session chair: Vytas Svedas, Moscow State University |
| 9:00 am - 9:35 am | selected poster presentations |
| 9:35 am - 10:10 am | Doug Cameron, Cargill
Engineering of a new metabolic system: the conversion of sugars to
3-hydroxypropionic acid |
| 10:10 am - 10:35 am | coffee break |
| 10:35 am - 11:10 am | Claudia Schmidt-Dannert, University of Minnesota
Engineering new biosynthetic pathways into recombinant cells for the production of complex chemical compounds |
| 11:10 am - 11:45 am | Greg Stephanopoulos, MIT
Application of metabolic engineering to indene biocatalysis for the biosynthesis of chiral drug precursors |
| 11:45 am - 12:00 pm | discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Future Trends in Biocatalysis |
| session chair: Marcel Wubbolts, DSM |
| 7:30 pm - 8:20 pm | Barry Marrs, Fraunhofer USA
What if industrial enzymes were free? |
| 8:20 pm - 9:10 pm | Mark Emptage, DuPont
The biorefinery concept: using biotechnology to shift from crude oil to plant feedstocks |
| 9:10 pm - 9:30 pm | discussion |
| Friday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |