Conference Program
 
LIPIDS, MOLECULAR & CELLULAR BIOLOGY OF

July 24-29, 2005
Waterville Valley Resort
Waterville Valley, NH

Chair:
Jean E. Vance

Vice Chair:
Charles E. Martin

The Molecular and Cellular Biology of Lipids Gordon Conference encourages the full participation of all attendees in the scientific activities of the meeting. All applicants, and especially those from under-represented demographics (i.e. women, minorities, junior investigators) are strongly encouraged to submit a brief abstract describing their work, and to indicate whether they would like their abstract to be considered for one of several short talks to be presented in each session. These short talks will be selected approximately 6 weeks prior to the conference, based on abstract submissions. Early application is encouraged since this conference is usually over-subscribed and the number of participants will be limited to 135. Please note that the conference venue has been changed to Waterville Valley.

SUNDAY
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pmSite Director's remarks
7:45 pmJean Vance (University of Alberta, Edmonton, Canada)
Chair's Welcome and Introduction
7:55 pm - 9:30 pmKONRAD BLOCH and EUGENE KENNEDY LECTURES
Discussion Leaders: Dennis E. Vance (University of Alberta, Edmonton) & Bill Dowhan (University of Texas, Houston)
7:55 pm Joseph Goldstein (University of Texas Southwestern, Dallas)
"The SREBP Pathway: Elucidation in Cultured Cells"
8:35 pm Michael Brown (University of Texas Southwestern, Dallas)
"The SREBP Pathway: Elucidation in Living Mice"
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCHOLESTEROL METABOLISM
Discussion Leader: Laura Liscum (Tufts University, Boston)
9:00 am David Russell (University of Texas Southwestern, Dallas)
"Molecular Mechanisms of Cholesterol Turnover in the Brain"
9:40 am Daniel Ory (Washington University, St. Louis)
"Niemann-Pick C Disease Genes and Cholesterol Homeostasis"
10:20 am Short talk selected from abstracts
10:30 amCoffee Break / Photo
10:50 amRussell DeBose-Boyd (University of Texas Southwestern, Dallas)
"Delineating the Pathway for Sterol-Accelerated Degradation of Mammalian HMG-CoA Reductase"
11:30 amRandy Hampton (University of California San Diego)
"Regulation of Protein Stability by Lipid-Mediated Reversible Misfolding"
12:10 pm Short talk selected from abstracts
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session #1
6:00 pmDinner
7:30 pm - 9:30 pmINTERORGANELLE LIPID TRANSPORT
Discussion Leader: Dennis Voelker (National Jewish Res. and Medical Center, Denver)
7:30 pm Masahiro Nishijima (National Inst. Infectious Diseases, Tokyo, Japan)
"Non-Vesicular Intracellular Trafficking of Ceramide by CERT"
8:10 pm Richard Pagano (Mayo Clinic and Foundation, Rochester)
"Coordinate Regulation of Caveolar Endocytosis and Secretory Processes by Sphingolipids and Cholesterol"
8:50 pm Gerrit van Meer (Utrecht University, the Netherlands)
"Fate and Function of Cellular Glycosphingolipids"
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmPHOSPHOLIPID METABOLISM
Discussion Leader: Suzanne Jackowski (St. Jude Children's Research Hospital, Memphis)
9:00 am Howard Goldfine (University of Pennsylvania, Philadelphia)
"Bacterial Phospholipases in Host-Pathogen Interactions"
9:40 am Rosemary Cornell (Simon Fraser University, Vancouver, Canada)
"Activation of CTP:phosphocholine Cytidylyltransferase by Membrane Binding"
10:20 amShort talk selected from abstracts
10:30 amCoffee Break
10:50 amNeale Ridgway (Dalhousie University, Halifax, Canada)
"An Intranuclear Membrane System Regulated by CTP:phosphocholine Cytidylyltransferase and Phosphatidylcholine Synthesis"
11:30 amArnold Strauss (Vanderbilt Children's Hospital, Nashville)
"Animal Models of a Human Mitochondrial Phospholipid Disorder: Barth's Syndrome"
12:10 pmShort talk selected from abstracts
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session #1
6:00 pmDinner
7:30 pm - 9:30 pmFATTY ACID METABOLISM - 1
Discussion Leader: Edward Dennis (University of California, San Diego)
7:30 pm Charles Martin (Rutgers University, New Jersey)
"Transcription and mRNA Stability: Regulation of Fatty Acid Desaturase Activities Through a Family of ER Membrane Proteins"
8:10 pm Thomas McIntyre (Cleveland Clinic, Cleveland)
"Metabolism of Oxidized Lipids and Mitochondrial Function"
8:50 pm William Smith (University of Michigan, Ann Arbor)
"Cyclooxygenases-1 and -2"
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmFATTY ACID METABOLISM - 2
Discussion Leader: Chuck Rock (St. Jude Children's Research Hospital, Memphis)
9:00 am John Cronan (University of Illinois, Urbana)
"ACP: New Stuff About an Old Protein"
9:40 am Diego de Mendoza (National University of Rosario, Argentina)
"Lipid Synthesis Regulated by a Transcription Factor Sensing Malonyl-CoA"
10:20 amShort talk selected from abstracts
10:30 amCoffee Break
10:50 amDavid Bernlohr (University of Minnesota, Minneapolis)
"Nutrient Sensing: Fatty Acid Transport in Adipocytes and Activation of AMP Kinase"
11:30 amJames Ntambi (University of Wisconsin, Madison)
"Role of Stearoyl-CoA Desaturase in Lipid Metabolism"
12:10 pmShort talk selected from abstracts
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session #2
6:00 pmDinner
7:30 pm - 9:30 pmABC TRANSPORTERS AND TRANSMEMBRANE LIPID FLUX
Discussion Leader: Chris Raetz (Duke University, Durham)
7:30 pm Peter Edwards (University of California Los Angeles)
"ABCG1: a Key Modulator of Lipid Flux"
8:10 pm Chip Davis (Schering-Plough Research Institute, Kenilworth)
"NPC1L1 Regulation of Intestinal Sterol Absorption"
8:50 pm Helen Hobbs (University of Texas Southwestern, Dallas)
"Trafficking of Dietary Cholesterol"
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTRIACYLGLYCEROL METABOLISM, OBESITY AND DIABETES
Discussion Leader: Rosalind Coleman (University of North Carolina, Chapel Hill)
9:00 amDawn Brasaemle (Rutgers University, New Jersey)
"Lipid Droplet-Associated Proteins and the Control of Triacylglycerol Metabolism in Adipocytes"
9:40 am Karen Reue (University of California, Los Angeles)
"Lipin: a Modulator of Triglyceride Metabolism in Adipose Tissue and Muscle"
10:20 amShort talk selected from abstracts
10:30 amCoffee Break
10:50 amHei-Sook Sul (University of California, Berkeley)
"Regulation of Fatty Acid and Fat Metabolism in Adipocytes"
11:30 amChris Newgard (Duke University, Durham)
"Mechanisms of Lipid-Induced Tissue Failure in Diabetes"
12:10 pmShort talk selected from abstracts
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session #2
6:00 pmDinner
7:30 pm - 9:30 pmTRANSCRIPTIONAL REGULATION OF LIPID METABOLISM
Discussion Leader: George Carman (Rutgers University, New Jersey)
7:30 pm Short talk selected from abstracts
7:40 pmBruce Spiegelman (Dana Farber Cancer Inst., Harvard Univ., Boston)
"Regulation of Lipid and Energy Homeostasis Through the PGC-1 Transcriptional Co-activators"
8:20 pmCarl Sparrow (Merck, Rahway)
"The LXR Nuclear Receptor and the Cellular Response to Excess Cholesterol"
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart
Last Updated: August 14, 2006