| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:00 pm | WELCOME AND KEYNOTE LECTURE |
| Joel Rosenbaum (Yale University, New Haven, CT)
"Intraflagellar Transport Moves Ciliary Membrane and Axonemal Proteins" |
| 9:00 pm - | Opening Reception in Ware Campus Center |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | FORCE PRODUCTION |
| Discussion Leader: Dan Kiehart (Duke University, Durham, NC) |
| 9:00 am - 9:20 am | Dan Kiehart (Duke University, Durham, NC)
"Biophysical and Genetic Analysis of Dorsal Closure Points to a Myosin Motor that Mediates Multiple, Redundant Forces for Morphogenesis" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Tom Pollard (Yale University, New Haven, CT)
"Control of Actin Filament Dynamics" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Tom Roberts (Florida State University, Tallahassee, FL)
"MSP-Based Leading Edge Protrusion, Cell Body Retraction, and Filopodial Extension" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break / Photo |
| 11:00 am - 11:20 am | Michael Sheetz (Columbia University, New York, NY)
"Cell Forces Act Locally by Substrate Activation of Srk Family Kinases but Signal Globally" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:40 am | Daniel A. Fletcher (UC Berkeley, Berkeley, CA)
"Force Microscopy of Growing Actin Networks In Vitro" |
| 11:40 am - 11:45 am | Discussion |
| 11:45 am - 11:55 am | Samara Reck-Peterson (UCSF, San Francisco, CA)
"Molecular Mechanism of Yeast Cytoplasmic Dynein" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Mohan Gupta (Dana Farber Cancer Institute, Boston, MA)
"Kip3, a Microtubule Motor and Depolymerase Required for Kar9-Dependent Spindle Positioning in Budding Yeast" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Stephanie L. Gupton (Scripps Research Institute, La Jolla, CA)
"Coupling the dynamics of the actin cytoskeleton to substrate adhesions and rapid cell migration in epithelial cells" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CENTROSOME |
| Discussion Leader: Tim Stearns (Stanford University, Stanford, CA) |
| 7:30 pm - 7:50 pm | Tim Stearns (Stanford University, Stanford, CA)
"Centriole Duplication During Ciliogenesis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:17 pm | Alexey Khodjakov (Wadsworth Center, Albany, NY)
"Centriole Replication: Born or Adopted?" |
| 8:17 pm - 8:25 pm | Discussion |
| 8:25 pm - 8:42 pm | Steve Doxsey (University of Massachusetts Medical School, Worchester, MA)
"Anchoring of Membrane Tethering and Fusion Proteins at the Midbody by the Centriolar Protein Centriolin is Required for Abscission During Cytokinesis" |
| 8:42 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:07 pm | David Agard (University of California, San Francisco, CA)
"Atomic Structure of Human Gamma-Tubulin and the Mechanism of Microtubule Nucleation" |
| 9:07 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Kenneth Sawin (Wellcome Trust Centre for Cell Biology, Edinburgh University, UK)
"Microtubule Nucleation in Fission Yeast" |
| 9:25 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | INTRACELLULAR MOVEMENTS |
| Discussion Leader: Lois Weisman (University of Iowa, Iowa City, IA) |
| 9:00 am - 9:20 am | Lois Weisman (University of Iowa, Iowa City, IA)
"An Organelle-Specific Myosin V Transport Complex" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | John Kendrick-Jones (MRC Laboratory of Molecular Biology, Cambridge, UK)
"Probing the Intracellular Functions and Motor Properties of Myosin VI" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Jon Scholey (University of California, Davis, CA)
"Intraflagellar Transport Motors in C. elegans Neurons" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:20 am | Robert Singer (Albert Einstein College of Medicine of Yeshiva University, Bronx, NY)
"Observing the Travels of Single mRNA Molecules" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | John Hammer (National Heart, Lung, and Blood Institute, Bethesda, MD)
"New Roles for Myosin V Receptor Components" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Tatsuhiko Noguchi (Washington University in St. Louis, St. Louis, MO)
"Myosin VI: an actin network stabilizer not a cargo transporter" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Trina Schoer (Johns Hopkins University, Baltimore, MD)
"A role for dynactin in tethering and coordinating signaling molecules" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CYTOSKELETAL DISEASES |
| Discussion Leader: Erika Holzbaur (University of Pennsylvania School of Medicine, Philadelphia, PA) |
| 7:30 pm - 7:50 pm | Erika Holzbaur (University of Pennsylvania School of Medicine, Philadelphia, PA)
"Dynactin Mutations in Motor Neuron Disease" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:17 pm | Tom Friedman (National Institute on Deafness and Other Communication Disorders, Bethesda, MD)
"Mutations of Myosin XVa and a co-Conspirator Cause Deafness by Arresting Hair Cell Stereocilia Uprisings" |
| 8:17 pm - 8:25 pm | Discussion |
| 8:25 pm - 8:42 pm | Frédéric Saudou (Institute Curie, Paris, France)
"Huntington's Disease: Function and Dysfunction of Huntingtin in Intracellular Transport" |
| 8:42 am - 8:50 pm | Discussion |
| 8:50 pm - 9:07 pm | Ronald Liem (Columbia University, New York, NY)
"Mutations in neurofilaments and plakins in neurodegenerative diseases" |
| 9:07 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Brett Lauring (Columbia University, New York, NY)
"Axons Sever to Survive: Spastin Mediated Microtubule Severing in Hereditary Spastic Paraplegia" |
| 9:25 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CELL POLARITY |
| Discussion Leader: Carole Parent (National Cancer Institute, Bethesda, MD) |
| 9:00 am - 9:20 am | Carole Parent (National Cancer Institute, Bethesda, MD)
"Cyclic AMP Metabolism and Directed Cell Migration" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Pierre Gönczy (Institut Suisse de Recherche Experiméntale sur le Cancer, Epalinges, Switzerland)
"Mechanisms of Asymmetric Cell Division in C. elegans Embryos" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Ian Macara (University of Virginia School of Medicine, Charlottesville, VA)
"Septins, Scribble, and Pars - Linking Polarity Proteins to the Cytoskeleton" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:20 am | Michael Dustin (NYU School of Medicine, New York, NY)
"Cytoskeletal Dynamics in T-cell Activation" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | David Drubin (University of California-Berkeley, Berkeley, CA)
"Harnessing Actin Dynamics for Endocytic Trafficking Events" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Julie Gates (University of North Carolina at Chapel Hill, Chapel Hill, NC)
"Ena Promotes Actin Filament Elongation during Drosophila Development" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Jan Faix (Institute for Biophysical Chemistry, Hannover, Germany)
"Formins and VASP Proteins Cooperate in the Formation of Filopodia" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session III |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | UNUSUAL CYTOSKELETONS AND HOST-PATHOGEN INTERACTIONS |
| Discussion Leader: Pascale Cossart (Institut Pasteur, Paris, France) |
| 7:30 pm - 7:50 pm | Pascale Cossart (Institut Pasteur, Paris, France)
"Exploitation of the Cytoskeleton by the Bacterial Pathogen Listeria monocytogenes" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:17 pm | David Sibley (Washington University School of Medicine, St. Louis, MO)
"Actin-Based Motility in Parasites" |
| 8:17 pm - 8:25 pm | Discussion |
| 8:25 pm - 8:42 pm | Isabelle Tardieux (Institut Cochin, Paris, France)
"How Does T. gondii Use Its Cytoskeleton to Parasitize Its Host-Cells?" |
| 8:42 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:07 pm | Matt Welch (University of California, Berkeley, CA)
"Role of Arp2/3 Complex-Mediated Actin Nucleation in Bacterial and Viral Pathogenesis" |
| 9:07 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Herwig Schuler (Stockholm University, Stockholm, Sweden)
"Dynamics and regulation of the actin cytoskeleton of Plasmodium" |
| 9:25 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CELL DIVISION |
| Discussion Leader: Claire Walczak (Indiana University, Bloomington, IN) |
| 9:00 am - 9:20 am | Claire Walczak (Indiana University, Bloomington, IN)
"Molecular Mechansisms of Mitosis - A Cellular Tug-of-War" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Kerry Bloom (University of North Carolina, Chapel Hill, NC)
"The Minus-End Directed Kinesin Kar3p Plays an Essential Role in Mitotic Chromosome Segregation and Karyogamy" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Don Cleveland (University of California, San Diego, CA)
"Guarding the Genome: Motors, Centromeres and the Mitotic Checkpoint" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am - 11:00 am | Coffee Break |
| 11:00 am - 11:20 am | Tarun Kapoor (Rockefeller University, New York, NY)
"Analyzing Proper Chromosome Segregation Using Chemical Biology" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | David Odde (University of Minnesota, Minneapolis, MH)
"Modeling of Kinetochore Microtubule Dynamics in Budding Yeast" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Liza Pon (Columbia University, New York, NY)
"Mitochondrial inheritance in Saccharomyces cerevisiae is required for cytokinesis and mitotic exit" |
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Duane Compton (Dartmouth Medical School, Hanover, NH)
"Efficient, but error-prone mitosis in human cells lacking poleward microtubule flux" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 6:00 pm | Free Time |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CYTOSKELETON AND CELL SIGNALLING |
| Discussion Leader: Gregg Gundersen (Columbia University, New York, NY) |
| 7:30 pm - 7:50 pm | Gregg Gundersen (Columbia University, New York, NY)
"Regulation of Microtubules by Rho GTPases in Migrating Cells" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:17 pm | Shuh Narumiya (Kyoto University Faculty of Medicine, Kyoto, Japan)
"Regulation of the Cytoskeleton by mDia Isoforms in Cell Motility and Division" |
| 8:17 pm - 8:25 pm | Discussion |
| 8:25 pm - 8:42 pm | Klaus Hahn (University of North Carolina, Chapel Hill, NC)
"New Approaches to Examine Signaling Activity in Living Cells - Rho GTPases and MAPK in Motility" |
| 8:42 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:07 pm | Rong Li (Harvard Medical School, Boston, MA and Stowers Institute for Medical Research, Kansas City, MO)
"Cytoskeleton and Signaling-Based Mechanisms for Spontaneous Cell Polarization in Budding Yeast" |
| 9:07 pm - 9:15 pm | Discussion |
| 9:15 pm - 9:25 pm | Anna Kashina (University of Pennsylvania, Philadelphia, PA)
"Posttranslational Arginylation Affects Actin Cytoskeleton and Cell Motility" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm - | Party in Ware Campus Center |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |