| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Opening lecture |
| 7:30 pm - 7:40 pm | Chair, Tracey Rouault
Welcoming Remarks |
| 7:40 pm - 8:30 pm | Bruce Spiegelman
Transcriptional control of mitochondrial biogenesis, respiration and oxidative stress through the coactivator PGC1 alpha |
| 8:30 pm - 8:45 pm | Discussion |
| 8:45 pm - | Chair's Reception: including wine-tasting from local winery |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Inflammation, oxidative stress and cardiovascular disease |
| 9:00 am - 9:10 am | Discussion Leader: Mark Gurney
Introduction |
| 9:10 am - 9:30 am | Mark Gurney
Leukotrienes, inflammation and genetic risk for heart attack and stroke in Iceland and the UK |
| 9:30 am - 9:40 am | Discussion |
| 9:40 am - 10:05 am | Garret FitzGerald
Arachidonic acid metabolism, atheroclerosis and oxidant stress |
| 10:05 am - 10:20 am | Discussion |
| 10:20 am - 10:45 am | Stan Hazen
Mechanisms linking myeloperoxidase, nitrative stress and atherosclerotic risks |
| 10:45 am - 11:00 am | Discussion |
| 11:00 am - 11:20 am | Coffee Break (Photo at 11:15) |
| 11:20 am - 11:45 am | Colin McPhee
LDL-cholesterol oxidation, and atherosclerosis |
| 11:45 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Paul Wentworth
Evidence for Ozone Production in Atherosclerosis |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session (presenters with last names that begin with A-L) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Mitochondria and oxidative stress |
| 7:30 pm - 7:40 pm | Discussion Leader: Ben Van Houten
Overview of session and biochemistry of mitochondrial reactive oxygen species |
| 7:40 pm - 8:05 pm | Douglas Green
Mitochondria, Reactive Oxygen, and Apoptosis: Twists and Turns on the Road to Ruin |
| 8:05 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:45 pm | David G Nicholls
The quantitative analysis of mitochondrial bioenergetics in stressed neurons |
| 8:45 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Speaker chosen from abstracts: Janine Santos
Telomerase and mitochondria: what is the connection? |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Reactive oxygen species and signaling pathways |
| 9:00 am - 9:10 am | Discussion Leader: Mary Dinauer
Overview of session and ROS signaling |
| 9:10 am - 9:35 am | Toren Finkel
Oxidants and aging |
| 9:35 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Rebecca Arnold
The Role of Nox1 and Reactive Oxygen in Prostate Cancer |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Coffee Break |
| 10:50 am - 11:15 am | Sue Goo Rhee
The sulfiredoxin-dependent reactivation of peroxiredoxins is a critical factor in determining cellular responses to oxidative stress |
| 11:15 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Jonathan Stamler
Nitrosative stress in disorders of the cardiovascular and respiratory systems |
| 11:55 am - 12:10 pm | Discussion |
| 12:10 pm - 12:20 pm | Short poster talk: TBA |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session (presenters with last names that begin with A-L) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | The role of nitric oxide in pathophysiology |
| 7:30 pm - 7:40 pm | Discussion leader: Solomon Snyder
The role of nitric oxide in pathophysiology |
| 7:40 pm - 8:05 pm | Lili Barouch
Mechanisms for Nitric Oxide Signaling Specificity in the Cardiovascular System |
| 8:05 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:45 pm | Mark Gladwin
Unraveling the reactions of NO, nitrite and hemoglobin in physiology and therapeutics |
| 8:45 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | C.S. Raman
NO Stress in Bacteria |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Misregulation of metal homeostasis and disease |
| 9:00 am - 9:10 am | Discussion Leader: Rod Levine
Overview |
| 9:10 am - 9:35 am | Valeria Culotta
The mitochondria, metals and oxidative stress |
| 9:35 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Michael Green
The lipocalin 24p3: Activities and Mechanisms |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Coffee Break |
| 10:50 am - 11:15 am | Tomas Ganz
Hepcidin, an inflammatory peptide implicated in pathogenesis of hemochromatosis |
| 11:15 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Speaker selected from abstracts: Wing Hang Tong
Iron-sulfur cluster biogenesis and mammalian mitochondrial iron homeostasis |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Speaker selected from abstracts: Jody Girouard
The CCS copper chaperone protects against misfolding of ALS-mutant SOD1 |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session (presenters with last names that begin with M-Z) |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| 7:30 pm - 9:30 pm | Oxidative stress in neurodegenerative disorders |
| 7:30 pm - 7:40 pm | Discussion Leader: Gary Fiskum
Oxidative stress and neurodegeneration |
| 7:45 pm - 8:05 pm | Massimo Pandolfo
Friedreich ataxia: abnormal iron-sulfur cluster biogenesis, mitochondrial iron overload, and neurodegeneration |
| 8:05 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:40 pm | Tom O'Halloran
A branch point in the human SOD1 maturation pathway leads to oxidative aggregation of fALS disease-causing variants |
| 8:40 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:15 pm | Nina Solenski
Nitrosative Stress in Acute and Chronic Neurodegenerative Disorders |
| 9:15 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Aging and oxidative stress |
| 9:00 am - 9:10 am | Discussion Leader: Simon Melov
Recent highlights in aging research |
| 9:10 am - 9:35 am | John Tower
Mechanism of life span extension by Drosophila MnSOD |
| 9:35 am - 9:50 am | Discussion |
| 9:50 am - 10:15 am | Thomas Nystrom
Defence against protein carbonylation; Role of both classical stress resistance networks and damage segregation inheritance of oxidatively damaged proteins during cytokinesis |
| 10:15 am - 10:30 am | Discussion |
| 10:30 am - 10:50 am | Coffee Break |
| 10:50 am - 11:15 am | John Phillips
Aging, dietary restriction, and the compartmentalization of reactive oxygen metabolism in Drosophila |
| 11:15 am - 11:30 am | Discussion |
| 11:30 am - 11:55 am | Holly van Remmen
Oxidative Stress and Aging: Insights from Mouse Models with Altered Antioxidant |
| 11:55 am - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Elissa Epel
The telomere/telomerase maintenance system: Links with psychological stress, oxidative stress, and risk for disease |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session (presenters with last names that begin with M-Z) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Keynote address |
| 7:30 pm - 8:30 pm | Solomon Snyder
Novel Neural Messengers and Cytoprotection |
| Reception to follow |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |