| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:15 pm | Welcome and Introduction |
| 7:30 pm - 9:30 pm | MOLECULAR MECHANISMS OF BYSTANDER EFFECTS |
| 7:30 pm - 7:40 pm | Discussion Leader: Bill Morgan (Bressler Research, University of Maryland) |
| 7:40 pm - 8:10 pm | Zelanna Goldberg (UC Davis Cancer Center)
"Humans as the Model System: Examining the Low Dose Radiation Response" |
| 8:10 pm - 8:40 pm | Kevin Prise (Gray Cancer Institute, Mt. Vernon Hospital)
"Mechanisms of the Bystander Response in Targeted Normal and Tumor Cells" |
| 8:40 pm - 9:10 pm | Yuri Dubrova (University of Leicester)
"The Offspring of Irradiated Parents. Why Are They Unstable?" |
| 9:10 pm - 9:30 pm | Selected Short Presentations / General Discussion |
| 9:30 pm - | Welcome Reception |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | GENOMIC APPROACHES TO UNDERSTAND RADIATION SENSITIVITY AND GENOMIC STABILITY |
| 9:00 am - 9:10 am | Discussion Leader: Martin Brown (Stanford University School of Medicine) |
| 9:10 am - 9:40 am | Sally Amundson (Columbia University)
"Gene Expression Profiling of Radiation Response in Human Cells" |
| 9:40 am - 10:10 am | David Hill (Dana Farber Cancer Institute)
"Metazoan Interactome Maps: Elucidating Properties of Complex Systems" |
| 10:10 am - 11:10 am | Coffee Break / Photo Session |
| 11:10 am - 11:40 am | James Brown (Stanford University)
"Clustering of Genome-Wide Quantitative Phenotypic Response Profiles and Maintenance of Genomic Fidelity to Determine Functional Pathways" |
| 11:40 am - 12:00 pm | Selected Short presentations |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | TARGETING SIGNALING PATHWAYS |
| 7:30 pm - 7:40 pm | Discussion Leader: Beverly Teicher (Genzyme Corporation) |
| 7:40 pm - 8:10 pm | Adam Dicker (Kimmel Cancer Center / Thomas Jefferson University)
"Tumor Microenvironment Modulate Radiosensitization to EGFR Blockade" |
| 8:10 pm - 8:40 pm | Mukesh Nyati (University of Michigan)
"Modulation of Extracellular Receptor Kinase (Erk) by Radiation - New Role of ATM Kinase" |
| 8:40 pm - 9:10 pm | Adrienne Cox (University of North Carolina at Chapel Hill)
"Regulation of Radiation Response by Ras and Rho Small GTPases" |
| 9:10 pm - 9:30 pm | Selected Short Presentations / General Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | RADIATION INDUCED MICROENVIRONMENT INTERACTIONS |
| 9:00 am - 9:10 am | Discussion Leader: Mary Helen Barcellos-Hoff (Lawrence Berkeley National Laboratory) |
| 9:10 am - 9:40 am | Eric Neilson (Vanderbilt University School of Medicine)
"Mechanisms of Tissue Fibrogenesis with Special Reference to EMT" |
| 9:40 am - 10:10 am | Valerie Weaver (University of Pennsylvania)
"Injury-Induced Spatial-Mechanical Regulation of Tissue Homeostasis" |
| 10:10 am - 10:40 am | Coffee Break |
| 10:40 am - 11:10 am | Eric Wright (University of Dundee, Ninewells Hospital)
"Microenvironmental and Genetic Factors Influencing Radiation Responses in the Hemapoietic System" |
| 11:10 am - 11:40 am | Andrei Gudkov (The Lerner Research Institute / Cleveland Clinic Foundation)
"Latent TGF2 and Other Modulators of NF-B as Radioprotectants" |
| 11:40 am - 12:00 pm | Selected short presentations |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | THE IMPACT OF ENDOTHELIUM ON TUMOR RESPONSE TO RADIATION |
| 7:30 pm - 7:40 pm | Discussion Leader: Richard Hill (Ontario Cancer Institute) |
| 7:40 pm - 8:10 pm | Mark Dewhirst (Duke University)
"Tumor-endothelial Cell Interactions: Evidence for Paracrine Survival as Influenced by hypoxia and Radiotherapy" |
| 8:10 pm - 8:40 pm | Richard Kolesnick (Memorial Sloan-Kettering Cancer Center)
"The Vascular Component of Tumor Response to High Dose Radiation" |
| 8:40 pm - 9:10 pm | Dennis Hallahan (Vanderbilt University)
"The Host Component of Cancer is a Biological Target for the Development of Radiosensitizers" |
| 9:10 pm - 9:30 pm | Selected Short Presentations / General Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | STEM CELLS IN REPAIR OF TISSUE INJURY |
| 9:00 am - 9:10 am | Discussion Leader: Joel Greenberger (University of Pittsburgh Cancer Institute) |
| 9:10 am - 9:40 am | Martin Korbling (UT MD Anderson Cancer Center)
"Sex-Mismatched Transplantation of Human Peripheral Blood-derived Stem Cells for Tissue Repair" |
| 9:40 am - 10:10 am | Joel Greenberger (University of Pittsburgh Cancer Institute)
"Molecular and Cellular Mechanisms of Radiation Pulmonary Fibrosis" |
| 10:10 am - 10:40 am | Coffee Break |
| 10:40 am - 11:10 am | Ross Summer (Boston University)
"The Study of Lung Vascular Progenitors" |
| 11:10 am - 11:40 am | David Piwnica-Worms (Washington University School of Medicine)
"Imaging Cell Trafficking and Protein-Protein Interactions" |
| 11:40 am - 12:00 pm | Selected short presentations |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DNA/HISTONE MODIFICATION AND RADIATION RESPONSE |
| 7:30 pm - 7:40 pm | Discussion Leader: Peggy Olive (British Columbia Cancer Research Center) |
| 7:40 pm - 8:10 pm | Phil Tofilon (National Cancer Institute)
"Histone Acetylation as a Target for Radiosensitization" |
| 8:10 pm - 8:40 pm | Markus Lobrich (University of Saarlandes)
"Repair of DNA Double-Strand Breaks at Low Radiation Doses" |
| 8:40 pm - 9:10 pm | Junjie Chen (Mayo Clinic College of Medicine)
"Signaling of DNA Damage Responses" |
| 9:10 pm - 9:30 pm | Selected short presentations / General Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | THE UBIQUITIN/PROTEASOME SYSTEM IM CANCER THERAPY |
| 9:00 am - 9:10 am | Discussion Leader: Bill McBride (UCLA Medical Center) |
| 9:10 am - 9:40 am | Brad Wouters (University of Maastricht)
"The Role of Novel Polyubiquitin Chains in Recovery from Replication Arrest" |
| 9:40 am - 10:10 am | Frank Pajonk (University of Freiburg)
"Proteasome Inhibition as a Means of Enhancing the Therapeutic Benefit of Cancer Therapy" |
| 10:10 am - 11:00 am | Coffee Break / Business Meeting |
| 11:00 am - 11:30 am | William Kaelin (Dana Farber Cancer Institute)
"VHL, HIF, And Cancer" |
| 11:30 am - 12:00 pm | Kelvin Davies (University of Southern California)
"Role of the Proteasome in Oxidative Stress" |
| 12:00 pm - 12:30 pm | Selected short presentations / General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | NOVEL ORGANISMS FOR STUDYING RADIATION RESPONSE |
| Discussion Leader: Richard Kolesnick (Memorial Sloan-Kettering Cancer Center) |
| 7:30 pm - 8:00 pm | John Abrams (University of Texas Southwestern Medical Center)
"Dying Like Flies: Radiation Induced Cell Death in a Genetic Model" |
| 8:00 pm - 8:30 pm | William Dynan (Medical College of Georgia, Institute of Molecular Medicine and Genetics)
"Radiation Injury and Radioprotection in the Zebra fish" |
| 8:30 pm - 9:00 pm | Joanne Weidhaas (Memorial Sloan-Kettering Cancer Center)
"Understanding EGFR/Ras-MAPK-Mediated Accelerated Repopulation Using a C.Elegans model" |
| 9:00 pm - 9:30 pm | James Maller (University of Colorado School of Medicine)
"Centrosomes, Cell Cycle Checkpoints, and Oncogenic Kinases: Xenopus as a Model System" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |