| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 4:00 pm - 6:00 pm | Opening Reception (Ware Campus Center) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | EARLY MEIOTIC EVENTS |
| Discussion Leader: Michael Lichten (National Cancer Institute) |
| 7:30 pm - 7:45 pm | David Page (Massachusetts Institute of Technology)
"The regulation of meiotic initiation in mice" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Alain Nicolas (Institute Curie)
"Targeted meiotic double-strand breaks formation in S. cerevisiae: mapping of Gal4BD-Spo11 cleavage sites and genome wide distribution" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Nancy Hollingsworth (SUNY Stonybrook)
"Cdc7 regulates DSB formation and meiotic progression in budding yeast" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:40 pm | Alistair Goldman (University of Sheffield)
"Analysis of resection at a meiosis-specific DNA double-strand break" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:00 pm | Tom Petes (Duke University)
"Meiotic DNA mismatch repair and recombination hotspots in yeast" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:20 pm | Dan Camerini-Otero (National Institutes of DDK, National Institutes of Health)
"The mouse Hop2 and Mnd1 proteins in meiotic recombination and recombination hotspots in humans" |
| 9:20 pm - 9:25 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | RECOMBINATION MECHANISMS |
| Discussion Leader: Neil Hunter (University of California, Davis) |
| 9:00 am - 9:20 am | Doug Bishop (University of Chicago)
"Genetic evidence for the synthesis-dependent strand-annealing model for meiotic non-crossover recombination" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Simon Boulton (London Research Institute)
"Meiotic functions of C. elegans BRCA1" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Anne Villeneuve (Stanford University)
"Global changes in chromosome organization coupled to key meiotic prophase events" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break / Group Photo |
| 11:15 am - 11:35 am | Patrick Sung (Yale University)
"Recombination Mediator Activity of a Human BRCA2-derived Polypeptide" |
| 11:35 am - 11:45 am | Discussion |
| 11:45 am - 12:05 pm | Charles White (Universite Blaise Pascal)
"Rad51 paralogs in Arabidopsis" |
| 12:05 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:35 pm | Gerry Smith (Fred Hutchinson Cancer Center)
"Single Holliday junctions are intermediates of meiotic recombination" |
| 12:35 pm - 12:45 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session A1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | MEIOTIC CHROMATIN AND EPIGENETICS |
| Discussion Leader: Angelika Amon (Massachusetts Institute of Technology) |
| 7:30 pm - 7:45 pm | Franz Klein (University of Vienna)
"Localization of Com1/Sae2 interactions with meiotic chromatin in yeast" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Bill Kelly (Emory University)
"Meiotic silencing in C. elegans" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Terry Orr-Weaver (Massachusetts Institute of Technology)
"Dynamic chromosome architecture and a histone code in meiosis" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:40 pm | Deborah Bourc'his (Institut Jacques Monod)
"Fate of retrotransposon transcripts in spermatocyctes" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:00 pm | Paul Burgoyne (National Institute for Medical Research)
"Why does chromosomal asynapsis in mammalian male meiosis lead to spermatocyte apoptosis?" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:20 pm | Jeannie Lee (Howard Hughes Medical Institute and Massachusetts General Hospital)
"Post-meiotic silencing in the male germline of the mouse: Implications for imprinted X-inactivation" |
| 9:20 pm - 9:25 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | PAIRING, CHROMOSOME DYNAMICS, AND SEGREGATION |
| Discussion Leader: Denise Zickler (University of Paris-Sud) |
| 9:00 am - 9:20 am | Nancy Kleckner (Harvard University)
"Motion and mechanics of meiotic chromosomes" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Abby Dernburg (Lawrence Berkeley National Lab)
"Pairing centers create an interface between chromosomes and the cytoskeleton to promote homologous pairing and synapsis" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Yasushi Hiraoka (Kansai Advanced Research Center)
"Homologous pairing in S. pombe" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 10:45 am - 10:55 am | Mike Dresser (Oklahoma Medical Research Foundation)
"Bouquet formation and function in S. cerevisiae" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:10 am | Dean Dawson (Oklahoma Medical Research Foundation)
"Roles for Centromere Pairing in Meiotic Chromosome Segregation in Budding Yeast" |
| 11:10 am - 11:15 am | Discussion |
| 11:15 am - 11:25 am | Eva Hoffmann (University of Sussex)
"Crossover proteins influence the segregation of non-exchange chromosome pairs in budding yeast" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Adela Calvente (Universidad Autonoma de Madrid)
"Synapsis and cohesin distribution in grasshopper metaphase-I chromosomes" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Scott Hawley (Stowers Institute)
"The Spindle Checkpoint and Achiasmate Segregation in Drosophila Oocytes" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session A2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | KINETOCHORES, MEIOTIC COHESION, AND SPINDLES |
| Discussion Leader: Pat Pukkila (University of North Carolina at Chapel Hill) |
| 7:30 pm - 7:45 pm | Sharon Bickel (Dartmouth College)
"Making and Breaking Meiotic Chromosome Cores" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Yoshinori Watanabe (Tokyo University)
"Shugoshin collaborates with PP2A to protect centromeric Rec8 at meiosis" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Angelika Amon (Massachusetts Institute of Technology)
"Establishing a meiosis I chromosome segregation pattern" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Bruce McKee (University of Tennessee)
"Meiotic cohesion in Drosophila" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Kim McKim (Rutgers University)
"Subito can promote spindle assembly in the absence of chromosomes in Drosophila oocytes" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:20 pm | Frank McNally (University of California, Davis)
"Control of Meiotic Spindle Length and Polar Body Size by a Microtubule-severing Enzyme" |
| 9:20 pm - 9:25 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SYNAPTONEMAL COMPLEX 50TH ANNIVERSARY CELEBRATION |
| Discussion Leader: Scott Keeney (Memorial Sloan-Kettering Cancer Center) |
| 9:00 am - 9:10 am | Montrose Moses (Duke University)
"The road to revealing the synaptonemal complex" |
| 9:10 am - 9:15 am | Discussion |
| 9:15 am - 9:35 am | Christa Heyting (Wageningen University)
"Cytological interference in three meiotic mutants of the mouse" |
| 9:35 am - 9:45 am | Discussion |
| 9:45 am - 10:05 am | Peter Moens (York University)
"Chiasma interference in the mouse - establishment of crossover sites and resolution of superfluous sites by the synaptonemal complex" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am - 10:25 am | Monica Colaiacovo (Harvard Medical School)
"Regulation of SC formation and chromosome segregation during C. elegans meiosis" |
| 10:25 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:10 am | Patricia Pukkila (University of North Carolina at Chapel Hill)
"Relationships between synapsis and crossing-over" |
| 11:10 am - 11:15 am | Discussion |
| 11:15 am - 11:35 am | Denise Zickler (University of Paris-Sud)
"The diffuse stage: exploration of events before and after in wild type and recombination plus sister-cohesion mutants of Sordaria" |
| 11:35 am - 11:45 am | Discussion |
| 11:45 am - 12:05 pm | Gareth Jones (University of Birmingham)
"Integration of chromosome synapsis and recombination in Arabidopsis thaliana" |
| 12:05 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Terry Hassold (Washington State University)
"Synapsis and crossing-over in the human male" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session B1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | CROSSOVER CONTROL I |
| Discussion Leader: Nancy Hollingsworth (SUNY Stonybrook) |
| 7:30 pm - 7:45 pm | Frank Stahl (University of Oregon)
"Two yeast crossover pathways differing in mismatch repair, Msh4-dependence, interference, and distribution among chromosomes" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Neil Hunter (University of California, Davis)
"Roles of RecQ Helicase Sgs1 in Regulating Meiotic Crossing-Over" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Michael Lichten (National Cancer Institute)
"Control of the crossover outcome of meiotic recombination" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Scott Keeney (Memorial Sloan-Kettering Cancer Center)
"Crossover homeostasis" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Barbara Meyer (University of California, Berkeley)
"Roles of dosage compensation genes in crossover control in C. elegans" |
| 9:05 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:20 pm | Hong Ma (The Pennsylvania State University)
"Identification and analysis of genes for crossover formation in Arabidopsis" |
| 9:20 pm - 9:25 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 9:00 am - 12:30 pm | CROSSOVER CONTROL II; REGULATION, CELL CYCLE CONTROL AND GAMETOGENESIS |
| Discussion Leader: Sharon Bickel (Dartmouth College) |
| 9:00 am - 9:20 am | Akira Shinohara (Osaka University)
"Spo16 promotes the imposition of crossover differentiation and couples crossover formation with chromosome synapsis during meiosis" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Bernard de Massy (Human Genetics Institute)
"Crossover and noncrossover pathways in mouse meiosis" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Paula Cohen (Cornell University)
"Differentiating the roles of the MutL homologs in mammalian meiosis" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 10:45 am - 11:05 am | Masayuki Yamamoto (University of Tokyo)
"Molecular mechanism to eliminate meiosis-specific mRNA selectively in growing fission yeast cells" |
| 11:05 am - 11:15 am | Discussion |
| 11:15 am - 11:25 am | Michael Primig (Biozentrum & Swiss Institute of Bioinformatics)
"Derepression of meiosis-specific genes in somatic malignancies" |
| 11:25 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Noriyoshi Sakai (National Institute of Genetics)
"In vitro development of Zebrafish germ cells" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Patricia Hunt (Washington State University)
"The environmental estrogen, bisphenol A disrupts meiotic prophase in the mammalian oocyte" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session B2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | EVOLUTION OF MEIOSIS AND SEX CHROMOSOMES |
| Discussion Leader: Mimi Zolan (Indiana University) |
| 7:30 pm - 7:45 pm | John Logsdon (University of Iowa)
"Natural history of meiosis genes and secret sex lives of eukaryotes" |
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | David Mark Welch (Marine Biological Laboratory)
"The Role of DNA Double-Strand Break Repair in Maintaining the Genome Structure of the Ameiotic Bdelloid Rotifers" |
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Bryant McAllister (University of Iowa)
"Effects of chromosomal rearrangements on patterns of recombination - insight into early stages of sex chromosome evolution" |
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Fernando Pardo-Manuel de Villena (University of North Carolina at Chapel Hill)
"The Om meiotic drive system - a model for identifying genes involved in nonrandom segregation of chromosomes during female meiosis" |
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:00 pm | David Kaback (UMDNJ-New Jersey Medical School)
"The Overall Distribution of Crossovers in Mammals and Yeast is Alike" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:20 pm | Zac Cande (University of California, Berkeley)
"Regulation of leptotene chromosome structure and function in maize" |
| 9:20 pm - 9:25 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |