| SUNDAY |
| 4:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DNA REPLICATION AND EXPRESSION |
| Discussion Leader: David Clayton (Howard Hughes Medical Institute) |
| 7:30 pm - 7:50 pm | Laurie Kaguni (Michigan State Univ.)
"Biochemical Genetics of the Mitochondrial Replicase" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Gerry Shadel (Yale Univ.)
"Multiple Functions of the Human Mitochondrial Transcription Machinery" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Sally MacKenzie (Univ. of Nebraska)
"Developmental Implications of Plant Mitochondrial Genome Instability in Higher Plants" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | David Stern (Cornell Univ.)
"Regulators of RNA Metabolism in the Chloroplast" |
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 8:00 am - 9:00 am | Breakfast |
| 9:00 am - 12:30 pm | PROTEIN IMPORT |
| Discussion Leader: Tom Fox (Cornell Univ.) |
| 9:00 am - 9:20 am | Trevor Lithgow (Univ. of Melbourne)
"Evolution of the Mitochondrial Protein Import Machinery" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Ophry Pines (Hebrew Univ.)
"Dual Targeting of Mitochondrial Proteins" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Klaus Pfanner (Univ. of Freiburg)
"The Mitochondrial Machinery for Import and Assembly of Proteins" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Group Photo / Coffee Break |
| 11:00 am - 11:20 am | Norbert Rolland (CEA Grenoble)
"An Alternative Plastid Targeting Pathway for a Protein Containing a Non-canonical Transit Peptide" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Arsenio Villarejo (Univ. of Madrid)
"A New Route through the Secretory Pathway for Proteins Targeted to the Plant Chloroplast" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Colin Robinson (Univ. of Warwick)
"Targeting of Thylakoid Lumen Proteins by the Tat Pathway" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ORGANELLE MORPHOLOGY AND MOVEMENT |
| Discussion Leader: Mike Yaffe (Univ. of California, San Diego) |
| 7:30 pm - 7:50 pm | Benedikt Westermann (Univ. of Bayreuth)
"Molecular Mechanisms of Mitochondrial Morphogenesis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Maureen Hanson (Cornell Univ.)
"Plant Organelle Movement and Dynamic Morphology" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Peter Hollenbeck (Purdue Univ.)
"Mitochondrial Transport and Activity in Axons" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Masamitsu Wada (National Institute for Basic Biology, Okazaki)
"The Importance and the Mechanisms of Chloroplast Photorelocation Movement" |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 8:00 am - 9:00 am | Breakfast |
| 9:00 am - 12:30 pm | PROTEIN COMPLEX ASSEMBLY AND PROTEOLYSIS |
| Discussion Leader: Steve Theg (Univ. of California, Davis) |
| 9:00 am - 9:20 am | Alex Tzagaloff (Columbia Univ.)
"Protein-dependent Assembly of Subunit 6 of Yeast Mitochondrial ATP Synthase" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Doron Rapaport (Ludwig-Maximilians Univ., Munich)
"Biogenesis of Mitochondrial Outer Membrane Complexes" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Francis-André Wollman (CNRS-IBPC, Paris)
"Limiting steps in the synthesis of chloroplast-encoded proteins" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am -11:20 am | Elzbieta Glaser (Univ. of Stockholm)
"A Novel Mitochondrial and Chloroplast Peptidasome" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am -11:50 am | Christiane Funk (Univ. of Umea)
"Chloroplast Proteases - a Comparison between Cyanobacteria, Annual Plant and Tree" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | Thomas Langer (Univ. of Cologne)
"Proteolytic Control of Mitochondrial Biogenesis" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | COFACTOR SYNTHESIS AND METAL HOMEOSTASIS |
| Discussion Leader: TBA |
| 7:30 pm - 7:50 pm | Catherine Clarke (Univ. of California, Los Angeles)
"A Multi-subunit High Molecular Mass Complex is Required for Yeast Coenzyme Q biosynthesis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Jerry Kaplan (Univ. of Utah)
"Regulation of Cellular Iron Acquisition by Mitochondrial Metal Metabolism" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Sabeeha Merchant (Univ. of California, Los Angeles)
"Essential Trace Metal Sparing in the Chloroplast" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Roland Lill (Univ. of Marburg)
"The Role of Mitochondria in Cellular Iron-sulfur Protein Biogenesis and Iron Homeostasis" |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 8:00 am - 9:00 am | Breakfast |
| 9:00 am - 12:30 pm | ORGANELLE DIVISION AND FUSION |
| Discussion Leader: TBA |
| 9:00 am - 9:20 am | Kathy Osteryoung (Michigan State Univ.)
"Towards a Mechanistic Model of Chloroplast Division" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Nobuhiro Tsutsumi (Univ. of Tokyo)
"Mitochondrial Fission and Fusion in Higher Plants" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Young Investigator Lecture: Simon Moller (Univ. of Stavanger, Norway)
"Dissecting Plastid Division in Arabidopsis" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:20 am | Janet Shaw (Univ. of Utah)
"Assembly and Function of Mitochondrial Fission Complexes in Yeast" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Rob Jensen (Johns Hopkins Univ. Medical School)
"Mitochondrial Division and Organelle Inheritance" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:20 pm | David Chan (Caltech)
"Cell-type Specific Functions of Mitochondrial Fusion in Mice" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DISEASE MECHANISMS |
| Discussion Leader: Eric Schon (Columbia Univ.) |
| 7:30 pm - 7:50 pm | Antonio Zorzano (Univ. of Barcelona)
"Role of Mitofusin-2 in Metabolic Diseases" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Bill Copeland (NIH)
"Disease Mutations in the Human Mitochondrial DNA Polymerase" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Massimo Zeviani (National Institute of Neurology, Italy)
"Disorders of mtDNA Maintenance and Integrity" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Eric Shoubridge (McGill Univ.)
"Defective Assembly of the Respiratory Chain and the Mystery of Tissue Specificity in Mitochondrial Disease" |
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 8:00 am - 9:00 am | Breakfast |
| 9:00 am - 12:00 pm | REGULATION AND SIGNALING |
| Discussion Leader: Jean-David Rochaix (Univ. of Geneve) |
| 9:00 am - 9:20 am | Xin Jie Chen (Univ. of Texas Southwestern Medical Center, Dallas)
"Regulating mtDNA Organization and Maintenance by Metabolic Signaling Pathways" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Lee Sweetlove (Univ. of Oxford)
"Maintaining Redox Balance in Plant Mitochondria" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Avi Danon (Weizmann Inst.)
"Regulatory Roles of Protein Disulfide Isomerase" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:20 am | Klaus Apel (ETH, Zurich)
"Singlet Oxygen-mediated Retrograde Signaling from the Chloroplast to the Nucleus" |
| 11:20 am - 11:30 am | Discussion |
| 11:30 am - 11:50 am | Rashu Seth (Univ. of Texas Southwestern Medical Center, Dallas)
"Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein" |
| 11:50 am - 12:00 pm | Discussion |
| 12:00 pm - 12:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | DEVELOPMENT AND AGING |
| Discussion Leader: Nils-Goran Larsson (Karolinska Institute) |
| 7:30 pm - 7:50 pm | Jane Langdale (Univ. of Oxford)
"Developmental Regulation of Chloroplast Biogenesis" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | David Logan (Univ. of St. Andrews)
"Plant Chondriome Structure, ROS, and Cell Death" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Nils-Goran Larsson (Karolinska Institute)
"Mitochondrial Dysfunction in Ageing and Parkinson´s Disease" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:15 pm | Concluding Remarks |
| FRIDAY |
| 8:00 am - 9:00 am | Breakfast |
| 9:00 am | Departure |